E-book
Versione Digitale
Rapoport, B.L. | Nayler, S. | Schmitt, F. | Troncone, G.

Fast Facts : Comprehensive Genomic Profiling : Making precision medicine possible

2020 - Karger Publishers

108 p.

  • Cancer is a multifaceted disease in which genetic changes induce uncontrolled tumor growth. Genomic characterization of cancer is now leading to better diagnostic, prognostic and predictive biomarkers, and effective individualized management. 'Fast Facts: Comprehensive Genomic Profiling' provides a crash course in the science, methods and application of genomic profiling. Assuming only the most basic knowledge - or memory - of cell biology, the authors provide an overview of DNA and RNA biology and next-generation sequencing. This sets in context the descriptions of prognostic and predictive biomarkers for different cancer types and genomic-based treatments. Finally, but importantly, some of the practicalities of gaining and interpreting genomic information are described. Whether you need a primer or a refresher, this short colorful book demystifies this complex subject. Contents: - Genetic mutations and biomarkers - Understanding next-generation sequencing - Elements of comprehensive genomic profile
  • s - Role in precision oncology - Predictive and prognostic biomarkers - Overcoming barriers to genotype-directed therapy [Publisher's text].
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